Idebenone hmoov

Idebenone hmoov yog ib qho organic compound, tsis tshua muaj insoluble nyob rau hauv dej, soluble heev nyob rau hauv chloroform, methanol los yog anhydrous ethanol, soluble nyob rau hauv ethyl acetate, insoluble nyob rau hauv hexane. Nws yog ib qho tshuaj txhawb nqa ntse tsim los ntawm Takeda kws Kev Lag Luam Co., LTD., Nyiv xyoo 1986. 

Nws yog ib qho tshuaj tshiab tshwj xeeb rau senile dementia thiab txhim kho lub hlwb ua haujlwm metabolism thiab cov tsos mob ntawm lub hlwb. Nws tuaj yeem ua rau mitochondrial muaj nuj nqi, txhim kho lub hlwb metabolism thiab lub hlwb tsis ua haujlwm, txhim kho kev siv cov piam thaj hauv lub hlwb thiab txhawb ATP ntau lawm. Nws tuaj yeem txhim kho cov metabolism ntawm neurotransmitter 5-hydroxytryptamine hauv hlwb, thiab muaj zog antioxidant thiab dawb radical scavenging nyhuv.  

Cov ntaub ntawv tseem ceeb ntawm Idebenone:

Dab tsi yog idebenone siv rau?

●Idebenone hmoov feem ntau yog siv rau cov kab mob Alzheimer, ib qho kev mob tshwm sim uas ua rau tsis pom kev (Leber hereditary optic neuropathy), thiab ib hom kev xeeb tub uas ua rau cov leeg tsis muaj zog thiab cov leeg tsis muaj zog (Duchenne cov leeg nqaij dystrophy). Nws tuaj yeem txhim kho cov tsos mob, yam lus, kev ntxhov siab, kev nyuaj siab, kev nco tsis tau, kev txawj ntse poob thiab lwm yam kev puas siab puas ntsws;

●Nws yog ib yam tshuaj tshiab rau senile dementia thiab txhim kho lub hlwb ua haujlwm metabolism thiab cov tsos mob puas hlwb;

●Nws tuaj yeem siv rau hauv cov khoom tu tawv nqaij:

★ Dawb radical tshem tawm:

Idebenone muaj qhov muaj peev xwm tshem tawm dawb ntawm ntau yam antioxidants. Nyob rau tib lub ntsiab lus, idebenone muaj peev xwm zoo sib xws ntawm DPPH thiab AAPH li dej-soluble vitamin E, thiab nws cov peev xwm tshem tawm ntawm ABTS dawb radical, tyrosine dawb radical thiab peroxynitro anion yog 50% ntawm dej-soluble vitamin E.

★ Kev tiv thaiv lub teeb puas:

★ Inhibits melanin ntau lawm:

Cov nyhuv inhibitory ntawm idebenone hmoov ntawm melanin tau zoo cuam tshuam nrog nws cov koob tshuaj. Cov nyhuv ntawm qhov siab ntawm idebenone zoo ib yam li hydroquinone. Tom qab qee qhov dilution, cov nyhuv inhibitory ntawm hydroquinone ntawm melanin ploj mus, thaum tsis tshua muaj siab ntawm idebenone tseem pom cov nyhuv inhibitory.